I am a senior research fellow and lecturer at the Computer Science department of ETH Zurich.
My research interests are in Bioinformatics, Evolutionary Genomics and Computational Molecular Evolution.
Together with my students I work on theoretical aspects of modeling molecular evolution as well as data-driven applications of our new methodologies. We are broadly interested in applying computational methods to study the process of gene and genome evolution and in particular the process of adaptive genetic change. Growing genome-scale sequences and information from complimentary disciplines of transcriptomics, proteomics and metabolomics have begun to seriously impact genomics. But the challenge of understanding the dynamics of such large-system data can only be met through an integration of organism, molecular, and mathematical disciplines. New techniques need to be developed for discovering complex patterns from multi-faced systems biology data.
Current research topics include:
My research activities are funded by grants from: